- Lipotropic compounds are those that help catalyse the breakdown of fat in the liver during metabolism in the body.
- CHOLINE is the major lipotrope in humans.
- A lipotropic nutrient promotes or encourages the export of fat from the liver. Lipotropics are necessary for maintenance of a healthy liver. Choline is essential for fat metabolism. Choline functions as a methyl donor and it is required for proper liver function.
- METHIONINE, an essential amino acid, is a major lipotropic compound in humans.
- Methionine levels also affect the amount of sulfur-containing compounds, such as glutathione, in the liver. Glutathione and other sulfur-containing peptides (small proteins) play a critical role in defending against toxic compounds.